Access to Accelerated Catalyst Testing

Did you know that we have more than 700 reactors for catalyst testing available in our laboratories in Amsterdam? This includes various high-throughput, multi-parallel catalyst testing platforms, both fixed-bed and batch.

What capabilities and expertise do we offer for our customers?

Type Example applications Reactors Reactor configuration Max Temperature in °C Max Pressure in bar Notes
Trickle-flow, heavy feed Hydrotreating
up to 16 4×4 500 180 Heated feed; Liquid product collection; Active
Liquid Distribution (ALD)
Gas phase Fischer Tropsch
Methane Activation
Ethane conversion
CO2 valorization
Selective hydrogenation
Selective Oxidation
up to 64 1×16
900 100 High-temperature options
Trickle flow / Gas phase, light feed Naphtha Reforming
Transalkylation (low sulfur feeds)
up to 16 1X16
550 100 Cooled feed; individual Reactor Temperature Control (iRTC);
Active Liquid Distribution (ALD)
Batch Parallel Reactors Hydrogenation
up to 72 1×12
200 160 Full batch or gas-on-demand; Identical gas feed per block;
Temperature control per block of 12 Rx
Our customers are looking for easy-to-access catalyst testing facilities to stay competitive. The majority of our in-house reactors is based on our unique Flowrence Technology platform. With this technology platform, we are able to perform parallel high-throughput catalyst testing tailored for the various R&D stages in line with our customer’s catalyst development objectives. No matter what R&D stage you are in – from early discovery to commercial evaluation – we generate outstandingly accurate and reproducible data for you. Hence, small changes in catalyst behavior can be readily detected and catalysts can be reliably differentiated.

What extra value do customers get?

Another valuable feature is the usefulness of the results – test results correlate with those from larger-scale experiments and even the data from commercial plants. Moreover, we have the ability to generate far more data than traditionally possible, leading to clearer and deeper insights into catalyst behavior and process performance. With our extensive in-house library of catalysts and supports, we can even amplify your Design-of-Experimentation or fill the blind spots.

We have many ways in which we can apply our capabilities and expertise to serve your R&D needs. How we do so, is entirely up to you. Our concern is that you benefit from enhanced technical decision-making, which ultimately translates into greater competitiveness and profitability.

What programs customer run with us?

Defined catalyst testing projects for short-term demands

Customers ask us to conduct well-defined catalyst testing projects, often part of more extensive R&D programs. We help them devise the most appropriate catalyst testing solutions in line with their specific objectives. We take pride in our ability to deal with short lead times and turn out results quickly.

High-throughput testing systems, both fixed-bed flow and batch are available for all R&D stages of the catalyst development. Different operating conditions can be varied in line with the requirements needed. Project duration can vary from just a few weeks up to multi-year programs

Long-term research collaborations

We are accustomed to working in integrated teams with customers to formulate experimentation strategies around specific R&D objectives and, ultimately, to deliver on them. These collaborations benefit from having (high-throughput) catalyst testing equipment, catalyst preparation with an extensive in-house library, well-qualified experts and a top-class data analytical capability, all under the same roof.

Our experts have a reputation for unconventional thinking and boast an impressive track record of developing novel approaches to seemingly intractable R&D challenges.

Our testing services can be supported by:

Obviously, catalyst and process IP stay with the customer with all services projects.

The Top 5 reasons why customers outsource their research to us

1. Long duration catalyst life testing 

Customers face various testing needs that compete with each other. Especially stability tests occupying testing equipment for a very long time, are often hampered by the limited availability of dedicated equipment. Customers outsource this type of testing to us and value it as reliable and cost-effective.

2. Extend capacity

This can vary from accommodating temporary single testing constraint up to long-term, dedicated multi-year testing programs. Avantium guarantees consistent and reliable data customers can believe in.

3. Optimize design-of-experimentation or solve exotic testing challenges

We have already found solutions to many exotic R&D challenges. For our experts, nothing’s off limits. We are known as unconventional thinkers with a resourceful way of working. Read a practical example around handling sensitive chemistry here.

4. Industrially scalable results

Refineries and chemical plants make their catalyst selection based on our testing results. They value that we are the leading independent testing company. Our testing facilities are also used in the process development phase and demonstrate high reproducibility with bench-scale reactors. More relevant data can be obtained safely in a shorter time at lower costs.

5. Staff constraints

The access to state of the art technology and well-qualified experts offers peace of mind. Effective collaboration is safeguarded by our focus on customer needs and objectives. We are easy to work with, result oriented and we deliver timely.

Single-Pellet-String-Reactors (SPSR)

No dead-zones, no bed packing & distribution effects. The catalyst packing is straightforward and does not require special procedures. A single string of catalyst particles is loaded in the reactors with an internal diameter (ID) that closely matches the particle average diameter. This applies to single catalyst systems, as well as stacked-bed systems. The use of a narrow reactor avoids any maldistribution of gas and liquid over the catalyst bed, thereby eliminating catalyst-bed channeling and incomplete wetting of the catalyst.

The most accurate and stable pressure regulator for 16-parallel reactors

The most accurate and stable pressure regulator for a multi-parallel reactors with just ±0.1bar RSD at reference conditions. The Reactor Pressure Controller (RPC) uses microfluidics technology to individually regulate the back-pressure of each reactor. By measuring the inlet pressure of each reactor, the RPC maintains a constant inlet pressure by regulating the backpressure. As a result, the distribution of the inlet flows over the 16 reactors is unaffected and a low reactor-to-reactor flow variability is achieved.

Reactor pressure control is not only important to ensure accurate pressure control, but also to help maintaining equal distribution of the inlet flow over the 16 reactors.

Automated liquid sampling system

Programmable, fully automated liquid product sampling robot for 24/7 hands-off operation. Robot equipped with a compact manifold aiming at depressurizing the effluent immediately after each reactor to atmospheric pressure. Reactor effluent is depressurized by a miniaturized (low volume) parallel dome regulator, allowing a stable control of gas or gas/liquid product streams. This eliminates the use of valves at high pressure (such as multi-position valves), which are prone to leakage.

Gas liquid separation is sone directly by collecting the liquid products in sample vials and directing the gas products to the online gas analyzer. This approach minimizes required flushing times in the downstream section of the reactor eliminating the need for high pressure gas-liquid separators, level sensors, and drain valves.

EasyLoad® reactor closing system

Unique reactor closing system, no connections required. With a rapid reactor replacement minimizing delays, improving uptime and reliability. Sealing of up to 16 reactors by simply closing the ‘top-box’ in a single action. No leak testing required!

Stable evaporation by liquid injection into reactor

The direct injection of liquid into the top of the reactor and the consecutive conditioning zone allows feeding of broad range of liquids and concentrations. Various types of liquids, both aqueous and oil phase are successfully evaporated and fed to the reactors.

Tube-in-tube reactor technology with effluent dilution

This unique tube-in-tube feature allows an easy and rapid exchange of the reactor tubes (within minutes!) with a single o-ring at the top of the reactor without the need for any connections. The use of an inert diluent gas (outside of reactor) to maintain the pressure stops undesirable reactions immediately after the catalyst bed while serving as a carrier gas to the GC, facilitating the analysis of high boiling point components, preventing dead volumes and back flow, and reducing the time required to transfer gas and liquid effluent products to the analytical instruments.

The tube-in-tube design enables the use of quartz reactors at high pressure applications.

Compact TinyPressure module glass-chip holder with integrated pressure measurement

Holds the microfluidic glass-chips for gas distribution and measures inlet (and outlet) pressure of the 16 parallel reactors at ambient temperature, allowing online measurement of catalyst bed pressure drop.

No high-temperature pressure sensors required. Pressure range of 10 – 200 bar (high pressure) or 0.5 – 10 bar (low pressure).

The modular design enables easy calibration and quick exchange of the microfluidic glass-chip, without the need for time-consuming leak testing.

Microfluidics modular gas distribution

Unrivalled accuracy in gas distribution with patented glass-chips for 4 and 16 reactors, tested with a guaranteed flow distribution of 0.5% RSD channel-to-channel variability. Quick exchange for different operating conditions, offering the unique flexibility to cover a wide range of applications using the same reactor system.

Auto-calibrating liquid feed distribution, measurement, and control

The most accurate liquid distribution for high throughput systems with real-time liquid flow measurement and control for 16-parallel reactors. Auto-calibrating function enabled by a single flow sensor guarantees that all 16 reactors are continuously operated at the desired LHSV, all the time. Innovative design based on our microfluidic glass-chips with integrated temperature-control. The system continuously regulates the liquid distribution to all 16 reactors, and together with our Reactor Pressure Control technology, eliminates the impacts of pressure variations in the flow distribution.

Proven technology with difficult feedstocks with high viscosity, such as VGO, HVGO and DAO: no blockage and or breakage observed. Different glass-chips available for different viscosities.

Liquid distribution errors below 0.2% RSD, making it the most accurate parallel liquid flow distribution device on the market.

Option to selectively isolate the liquid flow to any of the 16-parallel reactors.


Contact us

We are here to help you









Avantium Headquarters

+31 (0)20 586 8080

Zekeringstraat 29
1014 BV Amsterdam
The Netherlands

Contact us